Cardio Sigfried provides a database of randomized clinical trials in cardiology

Cardio Sigfried was designed in agreement with Evicardio Project to provide the clinician and investigator with a database of randomized clinical trials in cardiology, that may collaborate in the evidence based clinical practice.

The application includes four main tools

Clinical trials database

New data calculator

My trials (a personal database with new data)

Evidence based cardiology manual (only in Spanish)

1) Clinical trials database

The information may be consulted traditionally as abstracts, and more powerfully with two statistical "calculators":

a) Clinical trials events:

Evaluates drug/intervention trials with the parameters of evidence based medicine (EBM): statistical significance, absolute risk reduction (ARR), risk reduction (RR), relative risk reduction (RRR), number necessary to treat NNT, and odds ratio (OR);

b) Metaanalysis: to evaluate with the method of Mantel Hanszel Peto the main effect of series of clinical trials. Trials may be selected using 4 criteria of search (acronym, drug/intervention, therapeutic group, disease) and each event can be analyzed individually or in an overview grouping essays with similar designs. The analysis can be saved in your personal archive.

2) New data calculator

The app allows you to enter new trials in your personal database, using this two calculators (events in a single trial, metaanalysis of many trials and a third for Diagnostic tests: to evaluate diagnostic methods (sensitivity, specificity, positive and negative predictive value, likelihood ratio, post test) and also gives you the chance to change the prevalence in order to estimate the probability in different risk populations. All the data can be saved and accede afterwards in your personal database.

3) My trials

You can keep in your file new information read from the papers, or add to previous metaanalysis new data.

The app was developed by GEDIC. The original project leaders were Hernán Doval, Carlos Tajer y Juan Gagliardi. As coordinators Javier Mariani, Maximiliano de Andreu, Ignacio de Urquiza, Andres Rosende, Natalia Vensentini. Susana Lipshitz and Javier Marino. Cardiologists that help with the summaries: Adriana Acosta, Maria del Pilar Anoni, Mariela de los Santos, Laura Antonietti, Aníbal Arias, Laura Arias, Juan Bacigalupe, Maximiliano De Abreu, Rafael Feldman, Diego Funes, Javier Guetta, Luciano Lucas, Diego Manente, Walter Mason y Mariano Trevisan.

The computing-design and application was developed by Ariel Lichtin.

As secretaries, we had the huge help of Silvina Ruth Bravo and Gabriela Dominguez..

Cardio Sigfried in his agreement with EVICARDIO ® has copyright. The database will be updated periodically, and the information will be actualized through the platforms in IOS, Android and Blackberry. For questions our mail is [email protected].