CRRT -extrarenal purification-

Guide and dosage calculations for continuous renal replacement therapies.

The continuous renal replacement therapy (CRRT) are commonly used in ICU because acute kidney injury (AKI) is a serious and frequent process in the context of critically ill patients with multiple organ dysfunction syndrome. The techniques most commonly used are slow continuous hemodialysis and hemodiafiltration. This application contains indications, technical variations, calculation of initial dosing parameters, calculations of the filtration fraction and liquid replenishment for further adjustment, composition of fluid replacement and dialysis most commonly used and recommended doses of drugs to maintain extracorporeal circuit anticoagulation.

Introducing weight, hematocrit and liquid extraction times are calculated by the dose desired convection and diffusion (ultrafiltration ,dialysis) according to current recommendations (effluent <25 ml/kg/h), the blood flow necessary to maintain a filtration fraction <20% and the amount of fluid replenishment according to the chosen site of substitution (or postfilto prefilter). In the "adjustments" are calculated filtration fraction and liquid replacement according to selected parameters.